[3H]MRS2279

Ligand id: 1727

Name: [3H]MRS2279    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 5
Rotatable bonds 8
Topological polar surface area 208.77
Molecular weight 471.05
XLogP -1.73
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Parameter Concentration range (M) Reference
P2Y1 receptor Hs Antagonist Antagonist 8.1 pKd - 1
pKd 8.1 (Kd 8x10-9 M) [1]