Ligand id: 1756

Name: AR-C67085

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 7
Rotatable bonds 11
Topological polar surface area 324.63
Molecular weight 646.96
XLogP -3.35
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at Human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
P2Y12 receptor Antagonist Antagonist 8.2 pKd - 3
pKd 8.2 [3]
P2Y11 receptor Agonist Full agonist 8.5 pEC50 - 1-2
pEC50 8.5 [1-2]