Ligand id: 1877

Name: 15-deoxy-Δ12,14-PGJ2

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 54.37
Molecular weight 316.2
XLogP 5.34
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
DP2 receptor Hs Agonist Full agonist 8.5 pKi - 2
pKi 8.5 [2]
DP2 receptor Mm Agonist Full agonist 7.6 pKi - 1
pKi 7.6 [1]
DP1 receptor Hs Agonist Full agonist 6.6 pKi - 3
pKi 6.6 [3]
Ligand mentioned in the following text fields