BWA868C

Ligand id: 1897

Name: BWA868C

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 110.18
Molecular weight 459.27
XLogP 6.06
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
DP1 receptor Antagonist Antagonist 8.6 – 9.3 pKi - 1-2,4
pKi 8.6 – 9.3 [1-2,4]
Selectivity at mouse GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
DP1 receptor Antagonist Antagonist 6.7 pKi - 3
pKi 6.7 [3]