SB 242084

Ligand id: 193

Name: SB 242084

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 67.35
Molecular weight 394.12
XLogP 3.34
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
5-HT2C receptor Hs Antagonist Antagonist 8.2 – 9.0 pKi - 1-2
pKi 8.2 – 9.0 (Ki 6.31x10-9 – 1x10-9 M) [1-2]
5-HT2B receptor Hs Antagonist Antagonist 6.8 – 7.0 pKi - 1-2
pKi 6.8 – 7.0 [1-2]
5-HT2A receptor Hs Antagonist Antagonist 6.1 – 6.8 pKi - 1-2
pKi 6.1 – 6.8 [1-2]