Ligand Id: 194
Ligand name SB 243213

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 67.35
Molecular weight 428.15
XLogP 5.52
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

Selectivity data from IUPHAR-DB

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Receptor Type Action Affinity Units Concentration range (M) Reference
5-HT2B receptor Antagonist Antagonist 7.0 pKi - 1
5-HT2A receptor Antagonist Antagonist 6.8 pKi - 1
5-HT2C receptor Antagonist Antagonist 9.0 pEC50 - 1

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
For more details please contact: curators@iuphar-db.org