BMY 45778

Ligand id: 1963

Name: BMY 45778

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 98.59
Molecular weight 438.12
XLogP 7.4
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
IP receptor Hs Agonist Full agonist 8.0 pIC50 - 1
pIC50 8.0 (IC50 1x10-8 M) [1]