carbocyclic thromboxane A2

Ligand id: 1970

Name: carbocyclic thromboxane A2

Abbreviated name: CTA2

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 12
Topological polar surface area 57.53
Molecular weight 348.27
XLogP 7.21
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
TP receptor Agonist Full agonist 6.5 pKi - 1
pKi 6.5 [1]