pasireotide

Ligand id: 2018

Name: pasireotide

Structure and Physico-chemical Properties

2D Structure

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
SST2 receptor Rn Agonist Agonist 7.8 – 9.1 pEC50 - 1-2
pEC50 7.8 – 9.1 (EC50 1.75x10-8 – 8.6x10-10 M) [1-2]
SST2 receptor Rn Agonist Partial agonist 7.6 pEC50 - 2
pEC50 7.6 (EC50 2.33x10-8 M) [2]
SST2 receptor Rn Antagonist Antagonist <5.0 pEC50 - 1
pEC50 <5.0 (EC50 >1x10-5 M) [1]
SST5 receptor Hs Agonist Full agonist 9.8 pIC50 - 3
pIC50 9.8 [3]
SST2 receptor Hs Agonist Full agonist 9.0 pIC50 - 3
pIC50 9.0 [3]
SST3 receptor Hs Agonist Full agonist 8.8 pIC50 - 3
pIC50 8.8 [3]
SST1 receptor Hs Agonist Full agonist 8.0 pIC50 - 3
pIC50 8.0 [3]