sarpogrelate

Ligand id: 210

Name: sarpogrelate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 14
Topological polar surface area 85.3
Molecular weight 429.22
XLogP 4.51
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
5-HT2A receptor Hs Antagonist Antagonist 8.5 pKi - 4
pKi 8.5 [4]
5-HT2C receptor Hs Antagonist Antagonist 7.4 pKi - 4
pKi 7.4 [4]
5-HT2B receptor Hs Antagonist Antagonist 6.6 pKi - 4
pKi 6.6 [4]