tolyacetyl-c[DCys-Apa-DTrp-Orn-Val-Cys]-His-amide   Click here for help

GtoPdb Ligand ID: 2166

Comment: This synthetic peptide is an analogue of the conserved cyclic hexapeptide portion of urotensin-II (amino acids 5-10 of the endogenous peptide). A histidine replaces the valine in the carboxy terminal position 11 of the natural ligand.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
UT receptor Hs Antagonist Antagonist 7.7 pKd - 1
pKd 7.7 [1]