vasopressin

Ligand id: 2168

Name: vasopressin

Abbreviated name: AVP

Species: Human, Mouse, Rat

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Structure and Physico-chemical Properties

2D Structure

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Natural/Endogenous Targets
Target
OT receptor
V1A receptor
V1B receptor
V2 receptor
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
OATP3A1
Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
V1B receptor Agonist Full agonist 9.0 – 9.5 pKi - 1,3,7-8,10,12,14-15,17-18
pKi 9.0 – 9.5 [1,3,7-8,10,12,14-15,17-18]
V1A receptor Agonist Full agonist 8.5 – 9.3 pKi - 1,3,6-7,10-12,14-18
pKi 8.5 – 9.3 [1,3,6-7,10-12,14-18]
V2 receptor Agonist Full agonist 7.9 – 9.1 pKi - 1,3-4,7,10,12-15,17-18
pKi 7.9 – 9.1 [1,3-4,7,10,12-15,17-18]
OT receptor Agonist Partial agonist 7.3 – 9.3 pKi - 1-5,7-9
pKi 7.3 – 9.3 [1-5,7-9]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
V1B receptor Agonist Full agonist 9.9 pKi - 12
pKi 9.9 [12]
V1A receptor Agonist Full agonist 8.4 pKi - 4
pKi 8.4 [4]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Targets where the ligand is described in the comment field
Target Comment
Ligand mentioned in the following text fields