oxytocin

Ligand id: 2174

Name: oxytocin

Abbreviated name: OT

Species: Human, Mouse, Rat

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Structure and Physico-chemical Properties

2D Structure

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
OT receptor
V1A receptor
V1B receptor
V2 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
OT receptor Hs Agonist Full agonist 8.2 – 9.6 pKi - 1-6
pKi 8.2 – 9.6 [1-6]
OT receptor Rn Agonist Full agonist 8.7 pKi - 4
pKi 8.7 [4]
V1A receptor Hs Agonist Full agonist 6.9 – 8.3 pKi - 1,4,7-12
pKi 6.9 – 8.3 [1,4,7-12]
V1B receptor Hs Agonist Full agonist 5.7 – 7.0 pKi - 5,8-10,12
pKi 5.7 – 7.0 [5,8-10,12]
V2 receptor Hs Agonist Full agonist 5.4 – 6.8 pKi - 2,4,8-10,12
pKi 5.4 – 6.8 [2,4,8-10,12]
V1A receptor Rn Agonist Full agonist 6.1 pKi - 2
pKi 6.1 [2]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Targets where the ligand is described in the comment field
Target Comment
Ligand mentioned in the following text fields