oxytocin

Ligand id: 2174

Name: oxytocin

Abbreviated name: OT

Species: Human, Mouse, Rat

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Structure and Physico-chemical Properties

2D Structure

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Natural/Endogenous Targets
Target
OT receptor
V1A receptor
V1B receptor
V2 receptor
Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
OT receptor Agonist Full agonist 8.2 – 9.6 pKi - 1-6
pKi 8.2 – 9.6 [1-6]
V1A receptor Agonist Full agonist 6.9 – 8.3 pKi - 1,4,7-12
pKi 6.9 – 8.3 [1,4,7-12]
V1B receptor Agonist Full agonist 5.7 – 7.0 pKi - 5,8-10,12
pKi 5.7 – 7.0 [5,8-10,12]
V2 receptor Agonist Full agonist 5.4 – 6.8 pKi - 2,4,8-10,12
pKi 5.4 – 6.8 [2,4,8-10,12]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
OT receptor Agonist Full agonist 8.7 pKi - 4
pKi 8.7 [4]
V1A receptor Agonist Full agonist 6.1 pKi - 2
pKi 6.1 [2]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
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Target Comment
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