desmopressin

Ligand id: 2182

Name: desmopressin

Structure and Physico-chemical Properties

2D Structure

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
V2 receptor Rn Agonist Full agonist 8.7 pKi - 3
pKi 8.7 [3]
V1B receptor Rn Agonist Partial agonist 8.0 pKi - 7
pKi 8.0 [7]
V1B receptor Hs Agonist Full agonist 7.7 – 8.2 pKi - 1,5,7,10
pKi 7.7 – 8.2 [1,5,7,10]
V2 receptor Hs Agonist Full agonist 7.2 – 8.6 pKi - 1-3,5,7-10
pKi 7.2 – 8.6 (Ki 6.3x10-8 – 2.5x10-9 M) [1-3,5,7-10]
V1A receptor Hs Agonist Full agonist 7.0 – 7.7 pKi - 1,5-7,9-10
pKi 7.0 – 7.7 [1,5-7,9-10]
OT receptor Hs Agonist Full agonist 6.7 – 7.6 pKi - 2,4
pKi 6.7 – 7.6 [2,4]
V1A receptor Rn Agonist Full agonist 5.6 pKi - 2
pKi 5.6 [2]