desmopressin

Ligand id: 2182

Name: desmopressin

Structure and Physico-chemical Properties

2D Structure

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
V1B receptor Agonist Full agonist 7.7 – 8.2 pKi - 1,5,7,10
pKi 7.7 – 8.2 [1,5,7,10]
V2 receptor Agonist Full agonist 7.2 – 8.6 pKi - 1-3,5,7-10
pKi 7.2 – 8.6 (Ki 6.3x10-8 – 2.5x10-9 M) [1-3,5,7-10]
V1A receptor Agonist Full agonist 7.0 – 7.7 pKi - 1,5-7,9-10
pKi 7.0 – 7.7 [1,5-7,9-10]
OT receptor Agonist Full agonist 6.7 – 7.6 pKi - 2,4
pKi 6.7 – 7.6 [2,4]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
V2 receptor Agonist Full agonist 8.7 pKi - 3
pKi 8.7 [3]
V1B receptor Agonist Partial agonist 8.0 pKi - 7
pKi 8.0 [7]
V1A receptor Agonist Full agonist 5.6 pKi - 2
pKi 5.6 [2]