tamapin   Click here for help

GtoPdb Ligand ID: 2319

Synonyms: potassium channel toxin α-KTx 5.4
Comment: From Mesobuthus tamulus (Eastern Indian scorpion)
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
KCa2.2 Rn Channel blocker Antagonist 10.6 pIC50 - 1
pIC50 10.6 [1]
KCa2.3 Rn Channel blocker Antagonist 8.8 pIC50 - 1
pIC50 8.8 [1]
KCa2.1 Hs Channel blocker Antagonist 7.4 pIC50 - 1
pIC50 7.4 (IC50 4x10-8 M) [1]
Voltage: -100.0 – 40.0 mV