BIMU 8

Ligand id: 234

Name: BIMU 8

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 55.89
Molecular weight 342.21
XLogP 2.87
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
5-HT4 receptor Rn Agonist Full agonist 7.1 – 7.8 pKi - 1
pKi 7.1 – 7.8 [1]
5-HT4 receptor Mm Agonist Full agonist 7.4 pKi - 3
pKi 7.4 [3]
5-HT4 receptor Hs Agonist Full agonist 7.3 pKi - 2
pKi 7.3 (Ki 5.01x10-8 M) [2]