cinnamaldehyde

Ligand id: 2423

Name: cinnamaldehyde

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 17.07
Molecular weight 132.06
XLogP 3.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
TRPV3 Mm Activator Agonist - - 5x10-4 - 5x10-3 2
Conc range: 5x10-4 - 5x10-3 M [2]
Voltage: -80.0 – 80.0 mV
TRPA1 Mm Activator Agonist 4.2 pEC50 - 1
pEC50 4.2 (EC50 6.3x10-5 M) covalent [1]
Voltage: Physiological
Ligand mentioned in the following text fields