ACAA

Ligand id: 2443

Name: ACAA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 66.4
Molecular weight 337.17
XLogP 8.5
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
TRPM2 Channel blocker Antagonist 5.8 pIC50 - 1
pIC50 5.8 (IC50 1.7x10-6 M) [1]
Voltage: Physiological
TRPC3 Channel blocker - - - -
TRPC6 Channel blocker - - - -
TRPM8 Channel blocker - - - -