Ligand id: 2443

Name: ACAA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 66.4
Molecular weight 337.17
XLogP 8.5
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
TRPM2 Hs Channel blocker Antagonist 5.8 pIC50 - 1
pIC50 5.8 (IC50 1.7x10-6 M) [1]
Voltage: Physiological
TRPC3 Hs Channel blocker - - - -
TRPC6 Hs Channel blocker - - - -
TRPM8 Hs Channel blocker - - - -