DAU 6285

Ligand id: 246

Name: DAU 6285

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 71.11
Molecular weight 331.15
XLogP 2.36
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
5-HT4 receptor Hs Antagonist Antagonist 8.0 pKi - 1
pKi 8.0 [1]
5-HT4 receptor Mm Antagonist Antagonist 7.3 pKi - 2
pKi 7.3 [2]