DAU 6285

Ligand id: 246

Name: DAU 6285

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 71.11
Molecular weight 331.15
XLogP 2.36
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
5-HT4 receptor Antagonist Antagonist 8.0 pKi - 1
pKi 8.0 [1]
Selectivity at mouse GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
5-HT4 receptor Antagonist Antagonist 7.3 pKi - 2
pKi 7.3 [2]