diphenyltetrahydrofuran

Ligand id: 2498

Name: diphenyltetrahydrofuran

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 9.23
Molecular weight 224.12
XLogP 6.37
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at mouse ion channels
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Target Type Action Affinity Units Concentration range (M) Reference
TRPV3 Channel blocker Antagonist 5.0 – 5.2 pIC50 - 1
pIC50 5.0 – 5.2 (IC50 1x10-8 – 6x10-9 M) [1]
Voltage: -80.0 – 80.0 mV
Description: Patch clamp electrophysiology