Ligand id: 2498

Name: diphenyltetrahydrofuran

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 9.23
Molecular weight 224.12
XLogP 6.37
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
TRPV3 Mm Channel blocker Antagonist 5.0 – 5.2 pIC50 - 1
pIC50 5.0 – 5.2 (IC50 1x10-8 – 6x10-9 M) [1]
Voltage: -80.0 – 80.0 mV
Description: Patch clamp electrophysiology