ω-conotoxin MVIIC   Click here for help

GtoPdb Ligand ID: 2537

Synonyms: ω-CTx-MVIIC | SNX-230
Comment: From Conus magus (Magus cone or Magician's cone snail)
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Cav2.1 Rn Channel blocker Antagonist 8.2 – 9.2 pIC50 2x10-6 - 5x10-6 2
pIC50 8.2 – 9.2 (IC50 7x10-9 – 6x10-10 M) Conc range: 2x10-6 - 5x10-6 M [2]
Voltage: Physiological
Cav2.2 Rn Channel blocker Antagonist 6.1 – 8.5 pIC50 - 1-3
pIC50 6.1 – 8.5 (IC50 7.94x10-7 – 3.16x10-9 M) [1-3]
Voltage: -80.0 mV