ShK Toxin   Click here for help

GtoPdb Ligand ID: 2549

Synonyms: potassium channel toxin ShK | Stichodactyla helianthus toxin
Comment: From Stoichactis helianthus (Carribean sea anemone)
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Kv1.3 Rn Channel blocker - 9.9 – 12.0 pIC50 - 3-5
pIC50 9.9 – 12.0 [3-5]
Kv1.1 Rn Channel blocker - 10.8 pIC50 - 1
pIC50 10.8 [1]
Kv1.6 Rn Channel blocker - 9.8 pIC50 - 3
pIC50 9.8 [3]
Kv3.2 Hs Channel blocker - 9.5 pIC50 - 6
pIC50 9.5 [6]
Kv1.7 Mm Channel blocker - 7.9 pIC50 - 2
pIC50 7.9 [2]