α-dendrotoxin   Click here for help

GtoPdb Ligand ID: 2563

Synonyms: α-DTX
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Kv1.1 Rn Channel blocker - 7.7 – 9.0 pEC50 - 1,3
pEC50 7.7 – 9.0 (EC50 2x10-8 – 9.6x10-10 M) [1,3]
Kv1.2 Rn Channel blocker - 7.8 – 9.4 pIC50 - 1,3
pIC50 7.8 – 9.4 (IC50 1.7x10-8 – 3.8x10-10 M) [1,3]
Kv1.6 Hs Channel blocker - 7.7 pIC50 - 2
pIC50 7.7 (IC50 1.99x10-8 M) [2]