[3H]5-CT

Ligand id: 262

Name: [3H]5-CT    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 84.9
Molecular weight 203.11
XLogP 0.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
5-HT7 receptor Agonist Agonist 9.4 pKd - 2
pKd 9.4 (Kd 4x10-10 M) [2]
5-HT1D receptor Agonist Agonist 9.1 pKd - 4
pKd 9.1 (Kd 9x10-10 M) [4]
5-HT5A receptor Agonist Full agonist 8.6 pKd - 1
pKd 8.6 (Kd 2.5x10-9 M) [1]
5-HT6 receptor Agonist Agonist - - -
Selectivity at mouse GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
5-ht5b receptor Agonist Full agonist - - - 3
[3]