Ligand Id: 2630
Ligand name μ-conotoxin GIIIA


Summary Biological activity References Structure Similar ligands

Selectivity data from the Guide to Receptors and Channels (GRAC), 5th Edition.

Selectivity at human targets (unless otherwise stated)
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Receptor Type Action Affinity Units Concentration range (M) Reference
Nav1.4 Channel blocker - - - -

Selectivity data from IUPHAR-DB

Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Receptor Type Action Affinity Units Concentration range (M) Reference
Nav1.4 Pore Blocker Antagonist 5.9 pIC50 - 1
Selectivity at rat ion channels
Key to terms and symbols Click column headers to sort
Receptor Type Action Affinity Units Concentration range (M) Reference
Nav1.4 Pore Blocker Antagonist 7.3 – 7.7 pIC50 - 2-3

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
For more details please contact: curators@iuphar-db.org

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