BMS493

Ligand id: 2641

Name: BMS493

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 37.3
Molecular weight 404.18
XLogP 13.55
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Retinoic acid receptor-β Antagonist Inverse agonist 8.5 pIC50 - 1
pIC50 8.5 [1]
Retinoic acid receptor-α Antagonist Inverse agonist 8.4 pIC50 - 1
pIC50 8.4 [1]
Retinoic acid receptor-γ Antagonist Antagonist 7.0 pIC50 - 1
pIC50 7.0 [1]
Ligand mentioned in the following text fields