5-benzyloxytryptamine

Ligand id: 265

Name: 5-benzyloxytryptamine

Abbreviated name: 5-BT

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 51.04
Molecular weight 266.14
XLogP 3.97
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
5-HT6 receptor Rn Agonist Full agonist 6.5 – 7.2 pKi - 1-3
pKi 6.5 – 7.2 [1-3]
Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
TRPM8 Hs Channel blocker - - - -