AD-5061

Ligand id: 2663

Name: AD-5061

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 106.73
Molecular weight 408.11
XLogP 5.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Peroxisome proliferator-activated receptor-γ Agonist Full agonist 7.7 pIC50 - 1-2
pIC50 7.7 [1-2]
Peroxisome proliferator-activated receptor-α Agonist Agonist 5.6 pIC50 - 1-2
pIC50 5.6 [1-2]