pioglitazone

Ligand id: 2694

Name: pioglitazone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 93.59
Molecular weight 356.12
XLogP 3.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
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Target Sp. Type Action Affinity Units Concentration range (M) Reference
TRPM3 Hs Channel blocker - - - - 2
independent of PPAR-γ [2]
Selectivity at nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Peroxisome proliferator-activated receptor-γ Hs Agonist Full agonist 6.2 pIC50 - 1,4-5
pIC50 6.2 [1,4-5]