testosterone

Ligand id: 2858

Name: testosterone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 37.3
Molecular weight 288.21
XLogP 3.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Despite testosterone being an endogenous ligand, we have been unable to find molecular affinity data at the human androgen receptor.
Natural/Endogenous Targets
Target
Androgen receptor
Selectivity at rat nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Androgen receptor Agonist Agonist 7.8 pIC50 - 2
pIC50 7.8 [2]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Targets where the ligand is described in the comment field
Target Comment
Ligand mentioned in the following text fields