pitavastatin

Ligand id: 3035

Name: pitavastatin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 90.65
Molecular weight 421.17
XLogP 5.05
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
We have been unable to find publicly available bioactivity for this drug at its proposed human target, therefore we have not tagged a primary drug target in this instance.
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
hydroxymethylglutaryl-CoA reductase Rn Inhibitor Inhibition 5.1 pKi - 1
pKi 5.1 (Ki 8.9x10-6 M) [1]
Description: Note this assay used the pitavastatin calcium salt.