BAY 60-6583

Ligand id: 3289

Name: BAY 60-6583

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 164.11
Molecular weight 379.11
XLogP 1.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
A2B receptor Agonist Agonist 8.0 – 8.5 pKi - 1
pKi 8.0 – 8.5 (Ki 1x10-8 – 3x10-9 M) [1]
A1 receptor Agonist Agonist <5.0 pKi - 2
pKi <5.0 (Ki >1x10-5 M) [2]
A2A receptor Agonist Agonist <5.0 pKi - 2
pKi <5.0 (Ki >1x10-5 M) [2]
A3 receptor Agonist Agonist <5.0 pKi - 2
pKi <5.0 (Ki >1x10-5 M) [2]
Selectivity at mouse GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
A2B receptor Agonist Agonist 6.5 pKi - 2
pKi 6.5 (Ki 3.3x10-7 M) [2]