BAY 60-6583

Ligand id: 3289

Name: BAY 60-6583

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 164.11
Molecular weight 379.11
XLogP 1.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
A2B receptor Hs Agonist Agonist 8.0 – 8.5 pKi - 1
pKi 8.0 – 8.5 (Ki 1x10-8 – 3x10-9 M) [1]
A2B receptor Mm Agonist Agonist 6.5 pKi - 2
pKi 6.5 (Ki 3.3x10-7 M) [2]
A1 receptor Hs Agonist Agonist <5.0 pKi - 2
pKi <5.0 (Ki >1x10-5 M) [2]
A2A receptor Hs Agonist Agonist <5.0 pKi - 2
pKi <5.0 (Ki >1x10-5 M) [2]
A3 receptor Hs Agonist Agonist <5.0 pKi - 2
pKi <5.0 (Ki >1x10-5 M) [2]