Ligand Id: 3390
Ligand name 5S-HETE

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 14
Topological polar surface area 57.53
Molecular weight 320.24
XLogP 6.62
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Natural/Endogenous Targets
Target DB page
OXE receptor View in GRAC
View in IUPHAR-DB

Selectivity data from the Guide to Receptors and Channels (GRAC), 5th Edition.

Selectivity at human targets (unless otherwise stated)
Key to terms and symbols Click column headers to sort
Receptor Type Action Affinity Units Concentration range (M) Reference
TRPV1 Activator - - - -
Rank order of potency at human receptors (unless otherwise stated)
Description Rank order of potency Reference
Rank order of potency at OXE receptor 5-oxo-ETE, 5-oxo-C20:3 >> 5S-HPETE > 5S-HETE 1-3

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
For more details please contact: curators@iuphar-db.org