CL316243

Ligand id: 3462

Name: CL316243

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 8
Topological polar surface area 125.32
Molecular weight 421.09
XLogP 2.38
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
β3-adrenoceptor Agonist Agonist 5.2 pKi - 3
pKi 5.2 [3]
Selectivity at mouse GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
β3-adrenoceptor Agonist Agonist 5.9 pKi - 2
pKi 5.9 binding [2]
β3-adrenoceptor Agonist Agonist 8.7 – 9.8 pEC50 - 1-2
pEC50 8.7 – 9.8 cAMP accumulation [1-2]
Ligand mentioned in the following text fields