CP376395

Ligand id: 3496

Name: CP376395

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 34.15
Molecular weight 326.24
XLogP 6.11
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
CRF1 receptor Antagonist Antagonist 8.3 pIC50 - 1
pIC50 8.3 (IC50 5.01x10-9 M) [1]