sufentanil

Ligand id: 3534

Name: sufentanil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 61.02
Molecular weight 386.2
XLogP 4.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
μ receptor Agonist Full agonist 9.9 pKi - 1
pKi 9.9 (Ki 1.38x10-10 M) [1]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
μ receptor Agonist Full agonist 9.1 pKi - 2
pKi 9.1 (Ki 7.7x10-10 M) [2]