Ligand id: 364

Name: [3H]dimethyl-W84    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 15
Topological polar surface area 74.76
Molecular weight 576.37
XLogP 5.06
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
M2 receptor Hs Allosteric modulator Positive 8.5 pKd - 1
pKd 8.5 [1]
Ligand mentioned in the following text fields