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Synonyms: beta-defensin 2 | HBD2 | skin-antimicrobial peptide 1 (SAP1)
Compound class:
Endogenous peptide in human, mouse or rat
Comment: Human beta-defensin 4A is an antimicrobial peptide originally identified in psoriatic skin lesions [1]. It has potent antimicrobial activity against Gram-negative bacteria and the yeast Candida albicans but not the Gram-positive Staphylococcus aureus [1].
Species: Human
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| Bioactivity Comments |
| A study using a combination of recombinant β-defensins (1:1 ratio of hBD-1 and beta-defensin 4A) found promising in vivo activity against Salmonella enterica serovar Typhimurium, the pathogen that causes Typhoid Fever [2]. |
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