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Compound class:
Peptide or derivative
Comment: The peptide sequence given here (and the associated data) is for the shortest peptide analogue in the series which retained full binding to RXFP2 [1].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| Bioactivity Comments |
| Del Borgo et al (2006), produced a series of sequentially N- and C-terminally shortened linear analogues of the INSL3 βchain, and these were tested for binding to the RXFP2 receptor (LRG8 in the article) [1]. Table 1 provides the peptide sequence and binding assay results for each analogue. |
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