TSH   Click here for help

GtoPdb Ligand ID: 3920

Synonyms: Thyrogen® | thyroid-stimulating hormone | thyrotropin
Approved drug
TSH is an approved drug (FDA (1953))
Compound class: Endogenous peptide in human, mouse or rat
Comment: The drug thyrotropin alfa is a peptide heterodimer consisting of an α and β subunit and mimics the endogenous peptide hormone.
Species: Human
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: tsh

Natural/Endogenous Targets
Target
TSH receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
TSH receptor Primary target of this compound Ligand is endogenous in the given species Hs Agonist Agonist - - -
⤷
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Potency order of endogenous ligands at TSH receptor TSH (CGA, TSHB, P01215, P01222)
Ligand mentioned in the following text fields
Glycoprotein hormone receptors overview