BRL-54443

Ligand id: 3927

Name: BRL-54443

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 39.26
Molecular weight 230.14
XLogP 1.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
5-HT1F receptor Hs Agonist Full agonist 8.9 pKi - 1
pKi 8.9 [1]
5-ht1e receptor Hs Agonist Full agonist 8.7 pKi - 1
pKi 8.7 [1]