[3H]AZ11637326

Ligand id: 3971

Name: [3H]AZ11637326    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 25.36
Molecular weight 310.15
XLogP 3.84
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
nicotinic acetylcholine receptor α7 subunit Hs Agonist Full agonist 9.6 pKd - 1
pKd 9.6 (Kd 2.3x10-10 M) (α7)5 [1]