[3H]A-585539

Ligand id: 3974

Name: [3H]A-585539    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 29.02
Molecular weight 281.18
XLogP 3.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
nicotinic acetylcholine receptor α7 subunit Agonist Full agonist 10.1 pKd - 1
pKd 10.1 (Kd 7x10-11 M) native α7 [1]