Synonyms: Pavulon®
pancuronium is an approved drug (FDA (1990))
Compound class:
Synthetic organic
Comment: Pancuronium is a non-depolarizing curare-mimetic muscle relaxant, whose main action is as competitive acetylcholine antagonist at nicotinic acetylcholine receptors at neuromuscular junctions. Pancuronium is notoriously one of the components of the lethal injection in administration of the death penalty.
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Transporters Moving this Compound Across a Lipid Membrane | ||||||||
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Selectivity at ion channels | ||||||||||||||||||||||||||||||||||
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Additional information and targets (data relate to human unless otherwise stated) | ||
Description | Data | Reference |
Commonly used antagonists at nicotinic acetylcholine receptor α1 subunit | (α1)2β1γδ and (α1)2β1δε: α-bungarotoxin > pancuronium > vecuronium > rocuronium > tubocurarine (IC50 = 43 - 82 nM) |