ER819762

Ligand id: 4040

Name: ER819762

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 45.25
Molecular weight 489.3
XLogP 5.42
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
EP4 receptor Antagonist Antagonist 9.3 pKi - 1
pKi 9.3 (Ki 5.6x10-10 M) [1]
EP4 receptor Antagonist Antagonist 7.2 pIC50 - 2
pIC50 7.2 (IC50 7x10-8 M) [2]