Ligand id: 406

Name: [3H]DPCPX    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 69.3
Molecular weight 304.19
XLogP 3.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
A1 receptor Antagonist Antagonist 8.4 – 9.2 pKd - 1-5,7
pKd 8.4 – 9.2 (Kd 1.2x10-9 – 6x10-10 M) [1-5,7]
A2B receptor Antagonist Antagonist 7.4 pKd - 6
pKd 7.4 [6]
Ligand mentioned in the following text fields