aza-THIP

Ligand id: 4143

Name: aza-THIP

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 0
Topological polar surface area 60.94
Molecular weight 139.07
XLogP 0.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
GABAA receptor ρ1 subunit Hs Antagonist Antagonist - - -
[Binds to: GABA site]
GABAA receptor ρ2 subunit Hs Antagonist Antagonist - - -
[Binds to: GABA site]
GABAA receptor ρ3 subunit Hs Antagonist Antagonist - - -
[Binds to: GABA site]