carbenoxolone

Ligand id: 4151

Name: carbenoxolone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 117.97
Molecular weight 570.36
XLogP 6.86
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
VRAC Channel blocker - - - -
Cx23 Inhibitor - - - -
Cx25 Inhibitor - - - -
Cx26 Inhibitor - - - -
Cx30 Inhibitor - - - -
Cx30.2 Inhibitor - - - -
Cx30.3 Inhibitor - - - -
Cx31 Inhibitor - - - -
Cx31.1 Inhibitor - - - -
Cx31.9 Inhibitor - - - -
Cx32 Inhibitor - - - -
Cx36 Inhibitor - - - -
Cx37 Inhibitor - - - -
Cx40 Inhibitor - - - -
Cx40.1 Inhibitor - - - -
Cx43 Inhibitor - - - -
Cx45 Inhibitor - - - -
Cx46 Inhibitor - - - -
Cx47 Inhibitor - - - -
Cx50 Inhibitor - - - -
Cx59 Inhibitor - - - -
Cx62 Inhibitor - - - -
Px1 Inhibitor - - - -
Px2 Inhibitor - - - -
Px3 Inhibitor - - - -
Ligand mentioned in the following text fields