carbenoxolone

Ligand id: 4151

Name: carbenoxolone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 117.97
Molecular weight 570.36
XLogP 6.86
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
VRAC Hs Channel blocker - - - -
Cx23 Hs Inhibitor - - - -
Cx25 Hs Inhibitor - - - -
Cx26 Hs Inhibitor - - - -
Cx30 Hs Inhibitor - - - -
Cx30.2 Hs Inhibitor - - - -
Cx30.3 Hs Inhibitor - - - -
Cx31 Hs Inhibitor - - - -
Cx31.1 Hs Inhibitor - - - -
Cx31.9 Hs Inhibitor - - - -
Cx32 Hs Inhibitor - - - -
Cx36 Hs Inhibitor - - - -
Cx37 Hs Inhibitor - - - -
Cx40 Hs Inhibitor - - - -
Cx40.1 Hs Inhibitor - - - -
Cx43 Hs Inhibitor - - - -
Cx45 Hs Inhibitor - - - -
Cx46 Hs Inhibitor - - - -
Cx47 Hs Inhibitor - - - -
Cx50 Hs Inhibitor - - - -
Cx59 Hs Inhibitor - - - -
Cx62 Hs Inhibitor - - - -
Px1 Hs Inhibitor - - - -
Px2 Hs Inhibitor - - - -
Px3 Hs Inhibitor - - - -
Ligand mentioned in the following text fields