clomiphene

Ligand id: 4159

Name: clomiphene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 12.47
Molecular weight 405.19
XLogP 9.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
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Target Type Action Affinity Units Concentration range (M) Reference
VRAC Channel blocker - - - -
Selectivity at human nuclear hormone receptors
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Target Type Action Affinity Units Concentration range (M) Reference
Estrogen receptor-α Antagonist Antagonist 8.9 pKi - 1
pKi 8.9 (Ki 1.3x10-9 M) [1]