Ligand Id: 4205
Ligand name GSK1016790A

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 172.74
Molecular weight 654.11
XLogP 3.41
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

Selectivity data from the Guide to Receptors and Channels (GRAC), 5th Edition.

Selectivity at human targets (unless otherwise stated)
Key to terms and symbols Click column headers to sort
Receptor Type Action Affinity Units Concentration range (M) Reference
TRPV4 Activator - 8.7 pEC50 - 1

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
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